Pheromone Induces Programmed Cell Death in S. cerevisiae
نویسندگان
چکیده
منابع مشابه
Pheromone Induces Programmed Cell Death in S. cerevisiae
Programmed cell death is a ubiquitous process in multicellular organisms. The pathways by which cells in multicellular organisms trigger cell death have been extensively characterized. A typical scenario for programmed cell death development includes activation of the MAP kinase cascade, accumulation of reactive oxygen species, release of cytochrome c from mitochondria into cytoplasm as a conse...
متن کاملComment on Severin, F.F., and Hyman, A.A. (2002). Pheromone Induces Programmed Cell Death in S. cerevisiae. Curr. Biol. 12, R233–R235
This paper by Severin and Hyman [1] is the first to connect the social biology of yeast to yeast apoptosis. Pheromones of the mating pathway trigger yeast apoptosis as marked by DNA fragmentation and generation of oxygen radicals. Disruption of cytochrome c protects the cells from alpha factor-induced apoptosis, suggesting the involvement of the mitochondrial apoptotic pathway. During preparati...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2002
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)00776-5